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Leslie Mann Baffles Fans After Revealing Why Husband Judd Apatow Has Purposely Gained Weight While On Ozempic

Leslie Mann; Judd Apatow
ABC; Daniele Venturelli/WireImage

During a recent interview on Jimmy Kimmel Live!, Spa Day star Leslie Mann opened up about how her husband, director Judd Apatow, has purposely gained 15 lbs while on the "highest dose" of Ozempic for a truly bizarre reason.

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Leslie Mann is currently on a press tour for her latest film, Spa Weekend, during which she appeared on Jimmy Kimmel Live!

Mann was on the show opposite rap artist and guest host Jelly Roll, and while joking around with him, the subject of weight loss came up, which naturally reminded Mann of her husband, Judd Apatow.


Mann and Apatow have been married since 1997 and have two adult daughters. In recent years, Apatow has been prescribed Ozempic and is, based on Mann's account, on the "highest dose." But it isn't "working" the way people might expect.

Mann explained:

"He’s on Ozempic. He likes to talk about [it]."
"He has gained, like, 15 pounds in four years."
"He’s on the highest dose, and he likes to outrun the feeling that…Ozempic gives you to stop eating."
"He likes to override it or outrun it.”

Jelly Roll asked:

"He’s overeating Ozempic?"

With a sly look, Mann went on:

"He’s very proud of the fact that the pharmaceutical companies don’t have control over him!"

You can watch the clip here:

Ozempic has been approved by the FDA for diabetes, as well as preventive care for potential heart attacks. While Ozempic is frequently used for weight loss, especially among Hollywood actors and social media influencers, it has not been approved as a "weight loss" drug by the FDA.

It's unclear if Apatow has a history of diabetes or has the potential for heart problems, whether for hereditary or lifestyle reasons. But if he's taking it for weight loss, it seems it's bringing out a competitive edge in him rather than leading to actual weight loss.

Viewers were critical of the clip, pointing out how difficult it's becoming for people with diabetes to access the medication that's otherwise being given to wealthy people for weight loss purposes.

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While Mann's comments were received critically, it seems unlikely that she would mention a medication her husband was taking if he didn't have a valid reason to take it. Since he seems to be competing with pharmaceutical companies, it's unlikely that he's taking it for weight loss purposes and then bragging that it's not working.

However, it's still unfortunate that high-profile individuals are seemingly more able to access these medications because of their reputation and income, while their biggest fans may be struggling to get the treatments they need.

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