Skip to content
Search AI Powered

Latest Stories

Man Has 'Debilitating' Allergic Reaction To His Own Orgasms—And The Symptoms Can Sometimes Last Up To Two Weeks

The euphoric sensation achieved post coitus is undeniably something most of us relish and perhaps take for granted.

Not everyone experiences the highs derived from sex.


But for some, orgasms result in anxiety and depression.

A bizarre case of a millennial male experiencing allergic reactions from ejaculation was published in the March issue of the medical journal Urology Case Reports.

The anonymous 25-year-old from Massachusetts with the unfortunate ailment experienced "debilitating anxiety" and "brain fog" after climaxing.

He has been struggling with the symptoms since he was 16.

Doctors concluded the young man had post-orgasmic illness syndrome (POIS), a rare condition in which a person – primarily among men – experiences allergy and flu-like symptoms after orgasms, whether with a partner, through masturbation, or spontaneously during sleep.

Symptoms vary from person to person, but they may include "fatigue, weakness, headache, fever, mood changes, memory or concentration problems, stuffy nose, sore throat, and itching eyes."

Dr. Jose Bolanos, who treated the young man, said:

"Symptoms began at 16 years with sexual maturity and continued to the present time, regardless of whether ejaculation occurred via masturbation or intercourse with a female partner."
"For these reasons he avoided masturbation, and also attempted to avoid ejaculation when engaging in sex with a partner.

The patient's allergic symptoms incapacitated him to the extent where it affected his work and studies.

Giphy

Bolanos added:

"At the time of presentation he was single and orgasm frequency was once every two to three months."

Bolanos said that most doctors are unaware of the syndrome likely because patients with the symptoms choose not to seek medical attention.

"Due to lack of awareness of POIS as a medical entity, and with its component symptoms of anxiety, distress, and depressed mood, men with POIS may be first referred to a mental health professional, who also may be unfamiliar with this condition."


Dr. Abraham Morgentaler – director of Men's Health Boston and associate professor of urology at Harvard Medical School – said that POIS sufferers can experience symptoms immediately or with delay by two to three days for a period that can last as long as two weeks.

Fortunately, the patient eventually managed to find his happy ending thanks to a treatment of hormone replacement therapy through the use of human chorionic gonadotropin (HCG).

HCG is a hormone produced by women during pregnancy and, when injected in men, stimulates the testicles for more testosterone production.

After getting HCG injections three times a week, the doctor had excellent news for the patient's six-week followup.

"He ejaculated more frequently, and experienced no weakness, anxiety, brain fog, or malaise afterwards."
"He noted improved mood, overall energy, and libido."


Giphy

The young man told medics it was his first time having orgasms without physical and emotional distress since he was 16.

For him, such pleasures were a long time coming.

More from Trending

Woman crying
Photo by Fa Barboza on Unsplash

People Share The Wildest Thing Someone Said To Them When They Were In A Bad Place Emotionally

Content Warning: Depression, Grief, Miscarriage, Late Loved Ones, Child Abuse, Medical Negligence

Life is full of ups and downs, and sometimes, we'll be in very dark places, mentally or emotionally, and the last thing we need is to have someone figuratively rub salt in the wound.

Keep ReadingShow less

The Creepiest Unexplainable Things People Have Seen With Their Own Eyes

As much as we might not want to admit it, there are some things in life that are hard, if not impossible, to explain.

That's all the harder to swallow when the unexplainable is also horrifyingly creepy.

Keep ReadingShow less
Gavin Newsom; Screenshot of JD Vance from AI-generated video
Tayfun Coskun/Anadolu via Getty Images; @GovPressOffice/X

Gavin Newsom Just Epically Trolled JD Vance Over Tariffs With An AI Video About Couches

California Governor Gavin Newsom mocked Vice President JD Vance—and his love of couches—with an AI-generated video to troll him over the rising costs of goods due to President Donald Trump's retaliatory tariffs.

Earlier this week, Trump announced new tariffs: 10% on softwood timber and lumber, and 25% on “certain upholstered wooden products,” set to take effect October 14. The move follows Trump’s announcement last week of additional tariffs on kitchen cabinets, vanities, and other upholstered products, which will take effect October 1.

Keep ReadingShow less
Screenshots of Kelly Clarkson's conversation with bus drivers from Texas flood
The Kelly Clarkson Show/YouTube

Kelly Clarkson Honors Texas Flood Heroes In Emotional Return To Her Talk Show Following Ex's Death

In July 2025, homes, businesses, Camp Mystic, and more were swept away when central Texas was devastated with severe flooding. At Camp Mystic alone, 27 campers and staff members, including the camp's director, died during the initial flood.

Many people were caught off guard by the flooding and were left stranded mid-flood, getting to the highest ground they could find while they waited and hoped for help to come.

Keep ReadingShow less
Walton Goggins; Pete Davidson
Stephane Cardinale - Corbis/Corbis via Getty Images; Michael Loccisano/WireImage

Walton Goggins Speaks Out After Pete Davidson Predicts Fans Will 'Turn On' Him Like They Did Pedro Pascal

Pete Davidson went viral recently for calling out the weird online backlash to actor Pedro Pascal's unstoppable career trajectory in recent years.

And he thinks White Lotus star Walton Goggins is next.

Keep ReadingShow less